Have you ever read the label of a moisturizer or facial serum and come across two mysterious ingredients: Squalane e SqualaneYou may have wondered what the differences are between squalane and squalene and why they appear so often in natural beauty products. Both are oily substances, but they perform different functions and have unique characteristics. In this article, Nuvole di BellezzaWe'll delve into the world of these two much-talked-about ingredients, revealing their properties, their skin benefits, and which cosmetic products are most likely to contain them.

Why are Squalane and Squalene so loved?
Squalane (or Squalane) and Squalene are substances that are gaining more and more popularity in the world of cosmetics thanks to their beneficial properties for the skin. But why do we hear so much about them?
- Natural origin: Both Squalane and Squalene are derived from natural sources, making them cosmetic ingredients biocompatible and well tolerated by most people.
- Emollient and hydrating properties: Both help keep skin soft, supple and hydrated.
- Protective action: They can help strengthen the skin barrier by protecting it from external factors such as smog, wind and UV rays.
However, despite the similarities, Squalane and Squalene do have some substantial differences that are important to know to choose the right product for your skincare routine. Read on to find out everything you need to know about these two beauty allies!
What is Squalene?
Squalene is a natural compound found in human skin and in various animal and plant sources, such as olive oil and shark liver (yes, unfortunately you read that right but continue reading to learn more). It is an oily substance that keeps the top layer of the epidermis hydrated, preventing water evaporation. Thanks to its ability to mimic the skin's lipids, squalene helps keep the skin soft and hydrated.
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What is Squalane?
Squalane is a hydrogenated version of squalene, obtained through a process that makes the molecule more stable and resistant to oxidation. This chemical transformation is necessary because squalene is very unstable and oxidizes easily when in contact with air. Squalane, on the other hand, maintains the same hydrating properties as squalene, but with a longer shelf life of the product.

Difference Between Squalane and Squalene
The difference between squalane and squalene lies in the stability of the molecule. While squalene is very unstable and oxidizes quickly, squalane is a stable substitute for squalene. This makes squalane more suitable for use in cosmetic products, as it can last longer without deteriorating.
Let's get to know Squalene better: origin, properties and benefits for the skin
Definition and Origin of Squalene
Squalene is a natural component of our skin and can be derived from animal and plant sources. When squalene is produced synthetically or extracted from plant sources, such as olive oil, it becomes a key ingredient in natural and organic cosmetics. Squalene is similar to skin lipids, making it an effective ingredient for maintaining skin health.
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Properties of Squalene
- Moisturizing: Squalene is an excellent emollient moisturizer, able to penetrate the deep layers of the skin and retain water, keeping it soft and elastic.
- Emollient: It gives the skin a feeling of softness and smoothness, counteracting dryness and dehydration.
- Protective: It helps strengthen the skin barrier, protecting the skin from external agents such as smog, wind and UV rays.
- Antioxidant: Some research suggests that squalene may have antioxidant properties, counteracting the action of free radicals responsible for skin aging.
How Squalene Works on the Skin
Squalene exerts its beneficial action on the skin thanks to its unique chemical structure. Its affinity with human sebum makes it easily absorbed by the skin, where it acts as a true "natural oil". Penetrating into the deep layers, Squalene helps restore the skin's hydrolipidic balance, keeping it hydrated, soft and protected. In addition, its emollient property helps reduce flaking and combat skin dryness.
Limitations of Squalene
Despite its many benefits, Squalene has some limitations that hinder its use in cosmetics:
- Instability: Squalene is a chemically unstable compound and tends to oxidize easily upon contact with air and light, losing its beneficial properties and taking on a yellowish color.
- Comedogenicity: Some research suggests that Squalene may be comedogenic, meaning it may clog pores and cause blackheads and pimples. However, this is controversial and depends on several factors, such as skin type and product formulation.
Why is Squalene not always present in finished cosmetics?
Due to its instability and potential comedogenicity, Squalene is not always present in finished cosmetics. To overcome these problems, the cosmetic industry has developed a derivative of Squalene: Squalane.

Squalane: the stable derivative of Squalene
Definition and Production of Squalane
Squalane is a saturated aliphatic hydrocarbon, obtained through a hydrogenation process of Squalene. This process eliminates the double bonds of the Squalene molecule, making it more stable and resistant to oxidation.
Origin of Squalane
Vegetable squalane is obtained mainly from sources such asolive oil, rice bran and sugar cane. This choice makes squalane a sustainable and cruelty-free solution, unlike squalene extracted from shark livers. Using plant-based products is not only ethically correct, but also guarantees a more stable supply and less impact on the environment.
Properties of Squalane
- Emollient: Squalane retains the emollient properties of Squalene, giving the skin softness and smoothness.
- Moisturizing: Squalane also has a hydrating action, helping to keep the skin elastic and hydrated.
- Non-comedogenic: Unlike Squalene, Squalane is generally considered non-comedogenic, meaning it will not clog pores.
- Stable: Squalane is a chemically stable compound and resists oxidation, maintaining its beneficial properties over time.
Benefits of Squalane for the Skin
What are its benefits? Squalane is known for its moisturizing and protective properties. Some research also attributes squalene to a protective action against pathogens, thanks to the maintenance of a healthy skin barrier. Squalane is used in skin care products to prevent dryness, improve elasticity, and reduce the skin's susceptibility to skin disorders and skin cancer.
- Elasticity and softness: Squalane helps keep skin elastic and soft, counteracting dryness and dehydration.
- Protection: It helps strengthen the skin barrier, protecting the skin from external agents such as smog, wind and UV rays.
- Soothing: Squalane has soothing and calming properties, making it suitable for sensitive and irritated skin.
- Antioxidant: Some research suggests that squalane may have antioxidant properties, counteracting the action of free radicals responsible for skin aging.
Squalane in cosmetic products
Squalane has become a popular ingredient in cosmetics because of its ability to moisturize and protect the skin without clogging pores. Many skin care products, including serums, creams, and oils, contain squalane to improve skin hydration and texture. Because of its similarity to the skin's natural lipids, squalane is ideal for all skin types, including sensitive skin and baby skin.

Main Difference Between Squalane and Squalene: Oxidation Stability
The main difference between Squalane and Squalene lies in their stability to oxidation. Squalene, as we have seen, is an unstable compound that tends to oxidize easily upon contact with air and light, losing its beneficial properties and taking on a yellowish color. Squalane, on the other hand, thanks to the hydrogenation process, becomes a chemically stable compound that is resistant to oxidation, maintaining its beneficial properties over time.
Complete summary table on squalane and squalene
| Feature | Squalane | Squalane |
|---|---|---|
| Definition | Natural lipid found in human skin and various natural sources. | Hydrogenated version of squalene, more stable and resistant to oxidation. |
| Origin | It was once extracted mainly from shark livers; now plant sources such as olive oil and rice bran are preferred. | Derived mainly from plant sources such as olive oil, rice bran and sugar cane. |
| Stability | Very unstable, it oxidizes easily on contact with air. | Stable, does not oxidize easily, has a long shelf life. |
| Benefits for the Skin | It keeps the top layer of the epidermis hydrated, prevents dryness and improves skin elasticity. | Hydrates, protects and improves skin elasticity, preventing dryness without clogging pores. |
| Use in Cosmetic Products | Less frequently used due to its instability. | Widely used in serums, creams, oils and other skin care products. |
| Skin Compatibility | Similar to skin lipids, but less common in commercial products. | Highly compatible with all skin types, including sensitive and children's skin. |
| Sustainability | It can be extracted from animal sources (unsustainable) or plant sources (more sustainable). | Extracted mainly from plant sources, more sustainable and ethical. |
| Obtaining Process | Collected from natural sources, without further processing. | Obtained by hydrogenation of squalene to increase stability. |
| Antioxidant properties | High in natural antioxidants, but oxidizes easily. | It maintains antioxidant properties with greater stability. |
| Protective Barrier | Helps prevent moisture loss and protects against pathogens. | It forms a protective barrier that maintains hydration and protects the skin. |
| Protective action | They also attribute squalene a protective action against pathogens. | It helps to reduce dryness and prevent loss of elasticity. |
| Popularity in Modern Cosmetics | Less frequently used due to its instability. | Very popular in modern cosmetics for its properties and stability. |
How Squalane Hydrates Skin
Squalane hydrates the skin by slowing the evaporation of water and keeping the top layer of the epidermis hydrated. By maintaining an optimal level of hydration, the skin appears brighter and healthier. Topical application of squalane can help reduce dryness and prevent loss of elasticity.

What skin type is Squalane best suited for?
Squalane, due to its stability and non-comedogenicity, is generally considered suitable for all skin types, even sensitive and acne-prone skin. Its ability to moisturize and protect the skin makes it a valuable ingredient for the daily care of all skin types.
Is Squalane suitable for acne-prone skin?
Squalane is often recommended for acne-prone skin because of its soothing and non-comedogenic properties. Unlike some comedogenic oils that can clog pores and promote blackheads, Squalane does not clog pores and can help calm the inflammation that is typical of acne.
Focus on Squalane-based products
Squalane is a versatile ingredient that can be used in a variety of cosmetic products, including:
- Moisturizing creams: Squalane is a common ingredient in face and body moisturizers, where it helps keep skin hydrated, soft and protected.
- Anti-wrinkle serums: Squalane's antioxidant and hydrating properties make it a valuable ingredient in anti-wrinkle serums, where it can help combat the signs of skin aging.
- Face oils: Squalane can also be used as a pure facial oil for intense hydration and gentle skin protection.
- Hair products: Squalane can be added to conditioners and hair masks to add shine, softness and hydration to dry, damaged hair.

How to use squalane products
Squalane products can easily be incorporated into your skincare routine. You can apply pure squalane directly to your face after cleansing and before moisturizing. Alternatively, look for products that contain squalane as the main ingredient, to benefit from its hydrating and protective properties.
How to Find Squalane on the Ingredients Label (INCI)
Squalane is listed in the INCI (International Nomenclature of Cosmetic Ingredients) as “Squalane”. It is important to read the ingredient label carefully to ensure that the product contains pure Squalane and not Squalene.
Tips for choosing squalane products based on your needs
- Skin type: If you have dry skin, choose a product with a higher concentration of Squalane. If you have oily or combination skin, choose a product with a lower concentration.
- Other Ingredients: Pay attention to other ingredients in the product. If you have sensitive skin, avoid products with artificial fragrances or other potentially irritating ingredients.
- Budget: Squalane products can vary in price depending on the brand and the concentration of Squalane. Choose a product that fits your budget and meets your needs.
FAQ
Is Squalane an oil?
Squalane is a liquid hydrocarbon, but it is not really an oil in the traditional sense. It is more like an emollient that makes the skin feel soft and smooth.
Is Squalane Vegan?
Squalane can be of vegetal or animal origin. In particular, vegetal Squalane is obtained from vegetal sources such as olive oil or rice oil, while animal Squalane is obtained from animal sources such as shark liver. Let's say that modern cosmetics now prefer the use of vegetal squalane but from the inci it is not possible to know which type has been used. However, you can rely on the certification of vegan products for example
Is Squalane Safe to Use During Pregnancy?
There are no definitive scientific studies on the safety of Squalane during pregnancy. As a precaution, it is recommended to consult your doctor before using Squalane products during pregnancy or breastfeeding.
Can Squalane Clog Pores?
Squalane is generally considered non-comedogenic, meaning it should not clog pores. However, as with any cosmetic product, it is always advisable to do a patch test on a small area of skin before applying it to the face or other larger areas.
Are there alternatives to Squalane?
If you are looking for an alternative to squalane, you can try other non-comedogic plant oils such as jojoba oil, plant-derived squalene oil, or avocado oil.
Conclusions
Squalane and Squalene are both beneficial ingredients for the skin, but they have different characteristics and properties. Squalane, due to its stability and non-comedogenicity, is generally considered more versatile and suitable for all skin types. The choice between Squalane and Squalene depends on your specific needs and the type of product you are looking for. In any case, it is important to choose high-quality products and carefully read the ingredient label to ensure that you are using products that are safe and effective for your skin.
Final houghts
In conclusion, squalene and squalane are valuable ingredients for skin care, with proven benefits in skin hydration and protection. Here are the main points to remember:
- Difference between squalane and squalene: Squalane is a hydrogenated, more stable version of squalene.
- Benefits for the skin: Both ingredients moisturize and protect the skin, but squalane is preferred in cosmetics for its stability.
- Vegetable origin: Squalane can be obtained from sustainable sources such as olive oil and sugar cane.
- Use in cosmetic products: Squalane is ideal for all skin types, including sensitive skin and children's skin.
I hope this article has helped you better understand the differences between Squalane and Squalene and make informed choices for your skincare routine.
Leave a comment below if you have any additional questions or want to share your experience with Squalane or Squalene.
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